Optimal Immune Research Review
Chaga (Inonotus Obliquus) Extract: 30% Polysaccharides
Chaga mushroom extract inhibits oxidative DNA damage in human lymphocytes as assessed by comet assay.
https://www.ncbi.nlm.nih.gov/pubmed/15630179
Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus)
extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells.
https://www.ncbi.nlm.nih.gov/pubmed/20607061
Extract of Chaga mushroom (Inonotus obliquus) stimulates 3T3-L1 adipocyte differentiation
https://www.ncbi.nlm.nih.gov/pubmed/21031614
Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom,
Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae)
https://www.ncbi.nlm.nih.gov/pubmed/22135889
Chaga mushroom-induced oxalate nephropathy
https://www.ncbi.nlm.nih.gov/pubmed/23149251
Inhibitory effects of a polysaccharide extract from the Chaga medicinal mushroom, Inonotus obliquus
(higher Basidiomycetes), on the proliferation of human neurogliocytoma cells
https://www.ncbi.nlm.nih.gov/pubmed/24940902
A study of the antiherpetic activity of the chaga mushroom (Inonotus obliquus) extracts in
the Vero cells infected with the herpes simplex virus
https://www.ncbi.nlm.nih.gov/pubmed/25069286
Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”
https://www.ncbi.nlm.nih.gov/pubmed/25576897
Antiinflammatory and Immunomodulating Properties of Fungal Metabolites
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160565/
Chaga mushroom (Inonotus obliquus) induces G0/G1 arrest and apoptosis in human hepatoma HepG2 cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681140/
Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses
cancer progression and maintains body temperature in mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946216/
Cracked Shell Reishi Spores
Antiinflammatory and Immunomodulating Properties of Fungal Metabolites
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160565/
Ganoderma lucidum (Reishi) in cancer treatment
https://www.ncbi.nlm.nih.gov/pubmed/14713328
Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom
https://www.ncbi.nlm.nih.gov/pubmed/22593926
Ganoderma Lucidum (Reishi Mushroom) and cancer
https://www.ncbi.nlm.nih.gov/pubmed/27685898
The Pharmacological Potential of Mushrooms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1193547/
Recent developments in mushrooms as anti-cancer therapeutics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339609/
Anti-Tumor Effects of Ganoderma lucidum (Reishi) in Inflammatory Breast Cancer
in In Vivo and In Vitro Models
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585368/
Immune Modulation From Five Major Mushrooms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/
Turkey Tail (Coriolus Versicolor) Extract: 30% Polysaccharides
Discovery of novel xylosides in co-culture of basidiomycetes Trametes versicolor
and Ganoderma applanatum by integrated metabolomics and bioinformatics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018966/
Potential activities and mechanisms of extracellular polysaccharopeptides from fermented
Trametes versicolor on regulating glucose homeostasis in insulin-resistant HepG2 cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053205/
Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369477/
Trametes versicolor Mushroom Immune Therapy in Breast Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845472/
Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected
Trametes species from Serbia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118373/
Tramesan, a novel polysaccharide from Trametes versicolor
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567496/
Trametes versicolor Protein YZP Activates Regulatory B Lymphocytes – Gene Identification
through De Novo Assembly and Function Analysis in a Murine Acute Colitis Model
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760908/
Maitake (Grifola Frandosa) Extract: 30% Polysaccharides
Antiinflammatory and Immunomodulating Properties of Fungal Metabolites
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160565/
Immune Modulation From Five Major Mushrooms
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/
Effect of maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion
https://www.ncbi.nlm.nih.gov/pubmed/11995941
Can maitake MD-fraction aid cancer patients?
https://www.ncbi.nlm.nih.gov/pubmed/12126464
A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom)
in breast cancer patients: immunological effects
https://www.ncbi.nlm.nih.gov/pubmed/19253021
Immune enhancing effects of WB365, a novel combination of Ashwagandha
(Withania somnifera) and Maitake (Grifola frondosa) extracts
https://www.ncbi.nlm.nih.gov/pubmed/22540105
Immunomodulatory activities of medicinal mushroom Grifola frondosa extract
and its bioactive constituent
https://www.ncbi.nlm.nih.gov/pubmed/23336512
Genes related to suppression of malignant phenotype induced by
Maitake D-Fraction in breast cancer cells
https://www.ncbi.nlm.nih.gov/pubmed/23875900
Immune-enhancing effects of Maitake (Grifola frondosa) and Shiitake (Lentinula edodes) extracts
https://www.ncbi.nlm.nih.gov/pubmed/25332990
Antitumor activity of orally administered maitake α-glucan by stimulating
antitumor immune response in murine tumor
https://www.ncbi.nlm.nih.gov/pubmed/28278221
The effects of β-glucan on human immune and cancer cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704234/
Maitake mushroom extract in myelodysplastic syndromes (MDS)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317517/
Maitake Pro4X has anti‐cancer activity and prevents oncogenesis in BALBc mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055164/
Ashwagandha (Withania Somnifera) Root Extract (20:1)
Immune enhancing effects of WB365, a novel combination of Ashwagandha
(Withania somnifera) and Maitake (Grifola frondosa) extracts
https://www.ncbi.nlm.nih.gov/pubmed/22540105
Studies on the immunomodulatory effects of Ashwagandha
https://www.ncbi.nlm.nih.gov/pubmed/8866726
Studies on immunomodulatory activity of Withania somnifera (Ashwagandha)
extracts in experimental immune inflammation
https://www.ncbi.nlm.nih.gov/pubmed/10616957
In vivo effects of Ashwagandha (Withania somnifera) extract on the activation of lymphocytes
https://www.ncbi.nlm.nih.gov/pubmed/19388865
Molecular insight into the immune up-regulatory properties of the leaf extract of Ashwagandha
and identification of Th1 immunostimulatory chemical entity
https://www.ncbi.nlm.nih.gov/pubmed/19628058
A comparison of the immunostimulatory effects of the medicinal herbs Echinacea, Ashwagandha
and Brahmi
https://www.ncbi.nlm.nih.gov/pubmed/21619924
Dietary supplementation of Ashwagandha (Withania somnifera, Dunal) enhances NK cell function
in ovarian tumors in the laying hen model of spontaneous ovarian cancer
https://www.ncbi.nlm.nih.gov/pubmed/24188693
Effect of Withania somnifera (Ashwagandha) root extract on amelioration of oxidative stress and
autoantibodies production in collagen-induced arthritic rats
https://www.ncbi.nlm.nih.gov/pubmed/25803089
Immune System and Inflammation
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086159/
An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722/
P01.44. In vivo immune modulating effects of Ashwagandha (Withania somnifera)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373860/
Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory
endurance in healthy athletic adults
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687242/
Effect of a Novel Ashwagandha-based Herbomineral Formulation on Pro-inflammatory
Cytokines Expression in Mouse Splenocyte Cells: A Potential Immunomodulator
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407122/
Astragalus (Astragalus Membranaceus) Extract: 30% Polysaccharides
Enhancement of the immune response in mice by Astragalus membranaceus extracts
https://www.ncbi.nlm.nih.gov/pubmed/2149722
Immune system effects of echinacea, ginseng, and astragalus
https://www.ncbi.nlm.nih.gov/pubmed/15035888
Immune modulation of macrophage pro-inflammatory response by goldenseal and
Astragalus extracts
https://www.ncbi.nlm.nih.gov/pubmed/18800897
Astragalus embranaceus extract activates immune response in macrophages via heparanase
https://www.ncbi.nlm.nih.gov/pubmed/22695229
Astragalus membranaceus modulates Th1/2 immune balance and activates PPARγ in a murine
asthma model
https://www.ncbi.nlm.nih.gov/pubmed/25264079
Astragalus membranaceus: A Review of its Protection Against Inflammation and
Gastrointestinal Cancers
https://www.ncbi.nlm.nih.gov/pubmed/26916911
Natural Health Products, Modulation of Immune Function and Prevention of
Chronic Diseases
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297498/
Effects of Astragalus Polysaccharide on Immune Responses of Porcine PBMC
Stimulated with PRRSV or CSFV
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253776/
Burdock (Arctium Lappa) Root Extract (20:1)
Evaluation of the health aspects of methyl paraben: a review of the published literature
https://www.ncbi.nlm.nih.gov/pubmed/12387298
Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC)
https://www.ncbi.nlm.nih.gov/pubmed/17212569
Effects of drugs of plant origin on the development of the immune response
https://www.ncbi.nlm.nih.gov/pubmed/22238748
Burdock fructooligosaccharide induces stomatal closure in Pisum sativum
https://www.ncbi.nlm.nih.gov/pubmed/23911508
Burdock root extracts limit quorum-sensing-controlled phenotypes and biofilm architecture in
major urinary tract pathogens.
https://www.ncbi.nlm.nih.gov/pubmed/25226848
Effect of burdock extracts upon inflammatory mediator production
https://www.ncbi.nlm.nih.gov/pubmed/26684404
New Perspectives on Antiacne Plant Drugs
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132408/
Influence of Roasting Treatment on the Antioxidant Activities and Color of
Burdock Root Tea
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383138/
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