Studies Show Epimedium Helps Restore Nerves & Nervous System
Epimedium contains well over 50 different species, 5 of which are considered potently medicinal. Epimedium has garnered high praise and rigorous study for its benefits to circulation, hormone balance, reproductive health, and as an overall tonic for robust life force and health.
Both traditional knowledge of the plant and research aplenty make this an herb that is an absolute must-try for some of the most important facets of wellness in our day and age—and especially for the nervous system above all else.
A NERVE REGENERATOR OF THE HIGHEST DEGREE
One of the reasons epimedium gives those that eat it such boundless energy is because it’s been shown to literally regenerate and heal nerves.
2010 brought forth a study showing that the herb could literally help nerves grow back, in a process called “neurogenesis.” A couple years later in 2012, another study demonstrated that the icariin in epimedium could help restore movement in the body after a spinal cord injury.
And not only that: a 2015 study brought to light that it could also reduce chances of cognitive impairment, potentially making it effective in reducing the chances of dementia or Alzheimer’s disease. Among those facing onset of aging, this makes epimedium an invaluable herb to have on one’s side when growing older.
No wonder it was once called the brain tonic of the immortals. But it doesn’t end there—a very recent piece of 2017 research showed that epimedium could reinvigorate dead nerves and hair follicles in mice, which helped stimulate hair growth.
In short: epimedium may be an herb to help reinvigorate hair growth in instances of pattern baldness, a common obstacle many of us face as we age.
WHAT ELSE DOES EPIMEDIUM DO (AND HOW DOES IT WORK)?
Beyond the simple restoration of the nervous system, energy, and vitality, epimedium can do so much more for the body and for health.
To give a shortlist:
- Supports the nervous system
- Helps restore damaged nerves
- Balances both male and female hormones
- Enhances performance, stamina, and energy
- Reduces chances of reproductive dysfunction
- Improves circulation
- Combats stress burnout and adrenal fatigue
- Strengthens muscle and bone
- Protects as an antioxidant
Thousands of years after humans first noticed its romping effect on goats, we tried the herb to discover its effects on ourselves—and modern research has found some amazing things.
One of the most amazing discoveries is that epimedium contains icariin, a powerful flavonoid antioxidant compound.
And according to a 2015 review of the herb and its effects, icariin is the ultimate source of all its health wonders that benefit many levels of wellness in the body—and has an especially powerful impact on the nervous system above all other systems.
RESTORES MALE HORMONAL BALANCE
Going beyond the limits of its nervous tonic benefits, epimedium has astounded scientists in the way that it helps with hormones and reproductive health—and especially male health.
In a 2014 study on mice, icariin significantly boosted testosterone in test subjects, as well as boosting sperm count and fertility.
In yet another study much earlier in 2010, icariin appeared to go even further by preventing reproductive performance dysfunction in men. Apparently, the herb works much like a less powerful Viagra, all by inhibiting PDE5 (phosphodiesterase type 5), an enzyme that reduces blood flow.
Famous natural doctor Josh Axe has his own things to say about the wonder weed in his article on epimedium.
“…they enhance the effect of nitrous oxide (NO),” says Axe of PDE5 inhibitors like the icariin in epimedium.
“By increasing levels of nitric oxide, icariin helps to improve blood flow (circulation) by relaxing the smooth muscles of arteries, allowing more blood to reach the reproductive organs.”
ALSO, RESTORES FEMALE HORMONAL BALANCE
Before wondering why the herb skips out on the other equally important half of the population, brace for the following: yes, epimedium supports female reproductive health as well.
In a 2013 study, epimedium was found to directly help the body synthesize estrogen, which could be particularly helpful in instances where there is an abnormal lack of the hormone. This includes female health symptoms related to menopause, infertility, or other reproductive problems.
Epimedium is rich in prenylflavonoids, strongly antioxidant compounds that also act as phytoestrogens. Phytoestrogens, though they function a lot like and look like estrogens, are plant compounds that mimic human-produced estrogens.
When they enter the body, they fit in the exact same receptors that human-produced estrogens do and thus have the same effects on the body.
This makes epimedium an amazing potential remedy for issues having to do with women’s health—and perhaps even a step beyond. In a very recent 2016 study, it was found that its estrogen-boosting abilities could also in turn help prevent estrogen-related osteoporosis in women.
COMBATS LOW ENERGY, FATIGUE, AND STRESS
Male or female hormonal imbalance can certainly contribute to a lack of energy—and so can a weakened nervous system. Research suggests that epimedium can certainly help with both of the above.
And yet, epimedium can help recover the body in the face of stress burnout and fatigue in more ways than above. A 2013 study of epimedium’s effects showed that the herb may directly help regulate cortisol, a specific class of stress hormone.
When the body experiences any great deal of stress, it will release a lot more cortisol—and when too much cortisol circulates, this can cause adrenal fatigue, thyroid and endocrine imbalances, tiredness, low energy, and lots more subtle health problems.
Much like famous adaptogenic herbs—including ashwagandha, schisandra, and even gynostemma—epimedium restores energy and protects the body against stress just as effectively, and in more ways than one.
BOOSTS CARDIOVASCULAR HEALTH
Epimedium’s icariins are great for improving circulation, which can be a boon to men’s health. Taking a step back and looking at this in the sense of the bigger picture, better circulation doesn’t just mean better fertility and function: it also means a better, stronger heart and cardiovascular system overall.
A 2010 Chinese review of the herb points out its great potential as a remedy for heart-and blood vessel-related issues. These include hardening of the arteries, high blood pressure, irregular heartbeats, and of course heart attacks and heart failure.
Not to mention: in a 2011 trial on rats with heart failure, use of icariin helped reverse some of the heart failure’s worse symptoms. As a supplement, this makes epimedium a powerful protector for staying heart healthy!
INCREASING MUSCLE MASS
As mentioned earlier, epimedium increases circulation, which in turn has a marked effect on nitrous oxide production in the body.
And as many bodybuilders know full well: the more nitrous oxide gets created during a workout, the faster muscle is built in the body—and particularly lean, natural, and healthy muscle mass.
In fact, bodybuilders and other athletes looking to build muscle are huge fans of goat weed, and particularly its icariins. These flavonoids are responsible for the higher output of nitrous oxide created when the herb is taken.
Epimedium could be a great supplemental herb in those who are looking to build more muscle for whatever reasons they desire. What more: nitrous oxide production is often reduced greatly in those who are greatly stressed, hormonally imbalanced, or experiencing inevitable effects of aging.
Lucky for these people, epimedium also helps with these issues too—thus ensuring that nitrous oxide amounts are at optimal levels for the most natural, best muscle building results possible.
AN ENERGETIC HERB OF DISTINCTION—ESPECIALLY FOR MEN’S HEALTH
With all its virtues compared side-by-side, epimedium (or goat weed) is truly one of the most unique herbs out there for health.
Unlike other botanical remedies, it covers many different levels and aspects of wellness that simply don’t overlap within any other single herb. With such a special stature, it can be used to strengthen the body in the face of many wellness issues, especially common ones that happen to men as they age.
Its effects include:
- Boosting testosterone
- Improving focus and cognition
- Raising energy levels
- Enhancing performance and reproductive health
- Protecting heart health
- Increasing lean muscle mass
- Reinvigorating hair growth
Especially for men, epimedium may be the perfect herbal ally to have on one’s side when facing the inevitable—but manageable—effects of aging.
Not only can it restore balance to testosterone levels, thereby optimizing reproductive health, but it can also help build muscle, lose fat, boost heart health, increase focus, and restore thickness and luster in hair growth!
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Josh Axe (2017). Horny Goat Weed Benefits for Libido & Bone Health. DrAxe.com. Retrieved from https://draxe.com/horny-goat-weed/
Chenrui Li, Qiang Li, Qibing Mei, Tingli Lu (2015). Pharmacological effects and pharmacokinetic properties of icariin, the major bioactive compound in Herba Epimedii. Life Sciences 126(1) 57-68. Retrieved from http://www.sciencedirect.com/science/article/pii/S0024320515000442
Ruiqin Yao, Lan Zhang, Xiaoli Li, Lin Li (2013). Effects of Epimedium flavonoids on proliferation and differentiation of neural stem cells in vitro. A Journal of Progress in Neurosurgery, Neurology and Neurosciences 32(7) 736-742. Retrieved from http://www.tandfonline.com/doi/abs/10.1179/174313209X459183
Chihiro Tohda, Aiko Nagata (2012). Epimedium koreanum Extract and Its Constituent Icariin Improve Motor Dysfunction in Spinal Cord Injury. Evidence-Based Complementary and Alternative Medicine. Retrieved from https://www.hindawi.com/journals/ecam/2012/731208/abs/
Wen-Xian Li, Yuan-Yuan Deng, Fei Li, Bo Liu, Hui-Yu Liu, Jing-Shan Shi, Qi-Hai Gong (2015). Icariin, a major constituent of flavonoids from Epimedium brevicornum, protects against cognitive deficits induced by chronic brain hypoperfusion via its anti-amyloidogenic effects in rats. Pharmacology Biochemistry and Behavior Vol. 138 pp.40-48. Retrieved from http://www.sciencedirect.com/science/article/pii/S009130571530054X
Maoxin Chen, Jie Hao, Qiaozhen Yang, Gang Li (2014). Effects of Icariin on Reproductive Functions in Male Rats. Molecules 19(7) 9502-9514. Retrieved from http://www.mdpi.com/1420-3049/19/7/9502/html
Alan W. Shindel, MD; Zhong-Chen Xin, MD; Guiting Lin, MD, PhD; Thomas M. Fandel, MD; Yun-Ching Huang, MD; Lia Banie, BS; Benjamin N. Breyer, MD; Mauríce M. Garcia, MD; Ching-Shwun Lin, PhD; Tom F. Lue, MD (2010). Erectogenic and Neurotrophic Effects of Icariin, a Purified Extract of Horny Goat Weed (Epimedium spp.) In Vitro and In Vivo. The Journal of Sexual Medicine 7(4) 1518-1528. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2009.01699.x/full
Lijuan Yang, Danfeng Lu, Jiajia Guo, Xianli Meng, Guolin Zhang, Fei Wang (2013). Icarrin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19). Journal of Ethnopharmacology 145(3) 715-721. Retrieved from http://www.sciencedirect.com/science/article/pii/S0378874112008082
Feifei Xu, Yan Ding, Yingying Guo, Baoyue Liu, Zinong Kou, Wei Xiao, Jingbo Zhu (2016). Anti-osteoporosis effects of Epimedium via an estrogen-like mechanism based on a system-level approach. Journal of Ethnopharmacology 177(11) 148-160. Retrieved from http://www.sciencedirect.com/science/article/pii/S0378874115302087
Jianhua Huang, Jijun Li, Songbai Zheng, Junzhen Wu, Wei Zhang, Tao Sun, Sheilesh Kumar Dewan, Bill Kalionis, Ziyin Shen, Xiantao Tai, Shijin Xia (2013). Epimedium Flavonoids Counteract the Side Effects of Glucocorticoids on Hypothalamic-Pituitary-Adrenal Axis. Evidence-Based Complementary and Alternative Medicine. Retrieved from https://www.hindawi.com/journals/ecam/2013/938425/abs/
Xia Guo-lian, Huang Zhao-Quan (2010). Advances in Studies on Pharmacological Activities of Epimedium on Cardiovascular System. Chinese Archives of Traditional Chinese Medicine. Retrieved from http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZYHS201008046.htm
Yao-Hong Song, Hui Cai, Ning Gu, Chun-Fa Qian, Shou-Pei Cao, Zhi-Ming Zhao (2011). Icariin attenuates cardiac remodeling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure. Journal of Pharmacy and Pharmacology 63(4) 541-549. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.2010.01241.x/full
Y.-S. Su, Z.-X. Fan, S.-E. Xiao, B.-J. Lin, Y. Miao, Z. -Q. Hu, H. Liu (2017). Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells. Clinical and Experimental Dermatology 42(3) 287-294. Retrieved from http://onlinelibrary.wiley.com/doi/10.1111/ced.13043/full
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